AOD-96045mg
$110Lyophilized AOD-9604 supplied as a research reference standard.
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Supplied to qualified labs and institutional buyers. Institutional use & eligibility
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Example Certificate of Analysis
Certificate of Analysis
AOD-9604
Lot Number
EXAMPLE-LOT
Purity (HPLC)
≥99%
Nominal Fill
5mg
Illustrative example of the certificate format issued for this compound. Purity and specification figures are the published values for AOD-9604; the lot number and test date are placeholders, not a real result. The certificate for the specific lot you receive is matched to the lot number printed on the vial. For laboratory research use only.
Characteristics
| Molecular Formula | C₇₈H₁₂₃N₂₁O₂₃S₂ |
|---|---|
| CAS Number | 221231-10-3 |
| Molar Mass | 1815.08 g/mol |
| Amino Acid Sequence | Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe (hGH 176-191) |
| Synonyms | hGH Fragment 176-191, Anti-Obesity Drug 9604, AOD9604, Tyr-hGH 177-191 |
| Physical Form | Lyophilized powder |
| Solubility | Soluble in water and dilute acetic acid |
| Organoleptic Profile | White lyophilized powder; odorless |
| Storage Conditions | Store lyophilized at -20°C; reconstituted solution stable at 2-8°C |
| Composition | Lyophilized hGH fragment 176-191 acetate salt |
How is AOD-9604 used in research?
AOD-9604 is a 16-amino acid modified C-terminal fragment of human growth hormone (hGH 177-191 with an added N-terminal tyrosine), supplied as a lyophilized research standard for in-vitro lipolysis assays and receptor-binding studies. The sequence corresponds to the C-terminal lipolytic domain of hGH and is characterized in laboratory workflows as a receptor-selective reference compound distinct from full-length growth hormone.
In cell-culture systems, AOD-9604 is profiled in adipocyte lipolysis assays (glycerol-release readouts on 3T3-L1 or primary adipocyte cultures) and beta-3 adrenergic receptor-binding panels. Laboratory characterization includes receptor-selectivity profiling against IGF-1-mediated pathways to confirm the fragment's distinct binding signature. Not for use in any living organism.
Researchers use this compound as an analytical reference standard for HPLC identity and purity assays, LC-MS mass-accuracy work, and as a C-terminal hGH fragment reference in receptor-selectivity profiling across adipocyte cell-culture panels.
Areas of Study
In-Vitro Lipolysis Assays
Applied as a reference compound in glycerol-release and free-fatty-acid lipolysis assays on cultured adipocyte cell lines.
Receptor-Binding Studies
Profiled in competitive binding assays against beta-3 adrenergic receptor panels and IGF-1R reference panels for selectivity characterization.
Analytical Chemistry Reference
Used as an HPLC and LC-MS identity and purity reference standard for the 16-amino acid hGH C-terminal fragment.
Structural Characterization
Characterized by mass spectrometry and circular dichroism to confirm sequence identity and disulfide connectivity.
Receptor-Selectivity Profiling
Employed to differentiate C-terminal fragment binding patterns from full-length hGH reference ligands in cell-culture panels.
References
- [1]Ng FM, Sun J, Sharma L, et al. (2000). Metabolic studies of a synthetic lipolytic domain (AOD9604) of human growth hormone. Hormone Research, 53(6), 274-278.
- [2]Heffernan MA, Thorburn AW, Fam B, et al. (2001). Characterization of fat-oxidation markers in rodent models by chronic administration of human growth hormone or a modified C-terminal fragment. International Journal of Obesity, 25(10), 1442-1449.
- [3]Kwok HH, Mok DK, Chan PH, et al. (2012). Growth hormone fragment 176-191 in articular cartilage preclinical models. Osteoarthritis and Cartilage, 20(Suppl 1), S142.
Disclaimer: Information provided for research reference only; not medical advice. Sold strictly for in-vitro research use.
Certificate of Analysis
Third-party verified
Every batch of AOD-9604 is independently tested by an A2LA-accredited (ISO 17025:2017) laboratory using HPLC-UV/VIS for purity and identity, with a batch-specific lot number. Results are published publicly.
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Asked
Questions
Everything on purity, paperwork, shipping and the research-use-only terms. Still stuck? Read the full FAQ.
What does research use only mean?
Every compound we supply is a reference standard intended strictly for in-vitro laboratory research. It is not a drug or a supplement, and it is not for human or veterinary use, nor for diagnostic or therapeutic use.
How is purity verified?
Every lot is assayed by HPLC at an independent, accredited third-party laboratory. We publish the resulting Certificate of Analysis and link it to the lot number printed on the vial.
Where do I find the Certificate of Analysis?
Every lot has a public, batch-linked COA. Browse them all on the COA page, or open any product page and use the COA tab for that specific compound.
How quickly do orders ship?
Orders placed before 2PM EST ship the same business day. Shipments are cold-packed where required and fully tracked.
Do you ship internationally?
We currently ship within the United States. Requests from institutional buyers outside the US are handled case by case, so contact us before ordering.
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