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GH-Axis Receptor

CJC-1295 + Ipamorelin5mg + 5mg–10mg + 10mg

$100
In the vial:5-10mgCJC-1295 (No DAC)+5-10mgIpamorelin

Lyophilized CJC-1295 + Ipamorelin supplied as a multi-peptide research blend.

Size: 5mg + 5mg
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For laboratory research use only. Not for human or veterinary use. Not for diagnostic or therapeutic use.

Supplied to qualified labs and institutional buyers. Institutional use & eligibility

Frequently researched together

GLP-3 RT

GLP-3 RT

20mg

$150

KLOW

KLOW

80mg

$195

CJC-1295 + Ipamorelin

CJC-1295 + Ipamorelin

10mg + 10mg

$190

Bundle total

$535

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Example Certificate of Analysis

Certificate of Analysis

CJC-1295 + Ipamorelin

Lot Number

EXAMPLE-LOT

Purity (HPLC)

≥99%

Nominal Fill

5mg + 5mg

AppearanceLyophilized powder blend
Test Date
Testing LabIndependent Third-Party
PASS - Meets all specifications
Example Only

Illustrative example of the certificate format issued for this compound. Purity and specification figures are the published values for CJC-1295 + Ipamorelin; the lot number and test date are placeholders, not a real result. The certificate for the specific lot you receive is matched to the lot number printed on the vial. For laboratory research use only.

Characteristics

Characteristics of CJC-1295 + Ipamorelin
ComponentsCJC-1295 no DAC (Mod GRF 1-29) + Ipamorelin
CJC-1295 Molecular FormulaC₁₅₂H₂₅₂N₄₄O₄₂
Ipamorelin Molecular FormulaC₃₈H₄₉N₉O₅
CJC-1295 Molar Mass3367.97 g/mol
Ipamorelin Molar Mass711.85 g/mol
Physical FormLyophilized powder blend
SolubilityBoth components soluble in aqueous laboratory solvent
Organoleptic ProfileWhite lyophilized powder; odorless
Storage ConditionsStore lyophilized at -20°C; reconstituted solution stable at 2-8°C for up to 21 days
CompositionLyophilized blend of Modified GRF (1-29) acetate and Ipamorelin acetate

How is CJC-1295 + Ipamorelin used in research?

The CJC-1295 no DAC + Ipamorelin blend is a lyophilized research formulation combining a 30-amino acid GHRH analog (3367.97 g/mol) with a 5-amino acid synthetic pentapeptide (711.85 g/mol) for in-vitro receptor co-activation studies. The blend is supplied as a laboratory research standard targeting GHRH-R and GHS-R1a binding assays in parallel. Not for use in any living organism.

Characterization workflows profile the blend in recombinant GHRH-R and GHS-R1a expression systems, with standard biochemical readouts including cAMP accumulation (Gs-cAMP-PKA pathway) and IP1/calcium-flux panels (Gq/11-PLC-calcium pathway). In cultured pituitary somatotroph cell lines, the two components can be co-applied to study convergent signaling from the two receptor systems.

Researchers use this blend as a combined reference mixture for analytical method development (HPLC/LC-MS comparability assays requiring simultaneous quantitation of both peptides) and as a two-receptor co-activation reference for functional characterization of novel GHRH or GHS analogs.

Areas of Study

Two-Receptor In-Vitro Co-Activation Studies

Applied as a combined reference mixture for parallel GHRH-R and GHS-R1a binding and functional readouts in recombinant cell systems.

Convergent Signaling Characterization

Used to profile Gs-cAMP-PKA versus Gq/11-PLC-calcium pathway readouts simultaneously in cultured somatotroph cell lines.

Receptor Selectivity Profiling

Applied in multi-receptor panels to profile each component's selectivity signature within the two-component blend.

Analytical Method Development

Serves as a combined identity, purity, and potency reference standard in HPLC and LC-MS comparability workflows.

Structural Characterization

Used in mass-spectrometry and circular-dichroism profiling of the two-component lyophilized reference standard.

References

  1. [1]Bowers CY, Granda R, Mohan S, et al. (2004). Sustained elevation of pulsatile growth hormone (GH) secretion and insulin-like growth factor I (IGF-I) by a combination of the GH-releasing peptide-6 and GH-releasing hormone. Journal of Clinical Endocrinology & Metabolism, 89(10), 5174-5181.
  2. [2]Raun K, Hansen BS, Johansen NL, et al. (1998). Ipamorelin, the first selective growth hormone secretagogue. European Journal of Endocrinology, 139(5), 552-561.
  3. [3]Ionescu M, Frohman LA. (2006). Pulsatile secretion of growth hormone (GH) persists during continuous stimulation by CJC-1295, a long-acting GH-releasing hormone analog. Journal of Clinical Endocrinology & Metabolism, 91(12), 4792-4797.
  4. [4]Veldhuis JD, Keenan DM, Bailey JN, et al. (2008). Novel relationships of age, visceral adiposity, insulin-like growth factor (IGF)-I and IGF binding protein concentrations to growth hormone (GH) releasing-hormone and GH releasing-peptide efficacies in men during experimental hypogonadal clamp. Journal of Clinical Endocrinology & Metabolism, 93(6), 2143-2150.

Disclaimer: Information provided for research reference only; not medical advice. Sold strictly for in-vitro research use.

Certificate of Analysis

Third-party verified

Every batch of CJC-1295 + Ipamorelin is independently tested by an A2LA-accredited (ISO 17025:2017) laboratory using HPLC-UV/VIS for purity and identity, with a batch-specific lot number. Results are published publicly.

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Frequently Asked Questions

Everything on purity, paperwork, shipping and the research-use-only terms. Still stuck? Read the full FAQ.

What does research use only mean?

Every compound we supply is a reference standard intended strictly for in-vitro laboratory research. It is not a drug or a supplement, and it is not for human or veterinary use, nor for diagnostic or therapeutic use.

How is purity verified?

Every lot is assayed by HPLC at an independent, accredited third-party laboratory. We publish the resulting Certificate of Analysis and link it to the lot number printed on the vial.

Where do I find the Certificate of Analysis?

Every lot has a public, batch-linked COA. Browse them all on the COA page, or open any product page and use the COA tab for that specific compound.

How quickly do orders ship?

Orders placed before 2PM EST ship the same business day. Shipments are cold-packed where required and fully tracked.

Do you ship internationally?

We currently ship within the United States. Requests from institutional buyers outside the US are handled case by case, so contact us before ordering.

99%+ purityCOA per lotSame-day ship

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