Thymalin10mg
$80Lyophilized Thymalin supplied as a research reference standard.
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Example Certificate of Analysis
Certificate of Analysis
Thymalin
Lot Number
EXAMPLE-LOT
Purity (HPLC)
≥99%
Nominal Fill
10mg
Illustrative example of the certificate format issued for this compound. Purity and specification figures are the published values for Thymalin; the lot number and test date are placeholders, not a real result. The certificate for the specific lot you receive is matched to the lot number printed on the vial. For laboratory research use only.
Characteristics
| Molecular Formula | Polypeptide complex (heterogeneous mixture) |
|---|---|
| CAS Number | 63958-90-7 |
| Molar Mass | ~3108.50 g/mol |
| Amino Acid Sequence | 32-amino acid thymic polypeptide |
| Synonyms | Thymalin, Thymus extract peptide, Thymic factor |
| Physical Form | Lyophilized powder |
| Solubility | Soluble in water and physiological saline |
| Organoleptic Profile | White to off-white lyophilized powder; odorless |
| Purity | ≥95% by HPLC |
| Storage Conditions | Store lyophilized at -20°C; reconstituted solution stable at 2-8°C for up to 7 days |
How is Thymalin used in research?
Thymalin is a polypeptide complex originally isolated from the thymus gland, developed by Khavinson and colleagues at the Saint Petersburg Institute of Bioregulation and Gerontology. It belongs to a class of bioregulatory peptides that have been studied extensively in Russian biogerontology research for their effects on immune system restoration and aging. Thymalin is composed of a mixture of short peptides derived from thymic tissue and has been investigated for its ability to restore thymic function and modulate immune competence in aging and immunodeficiency models.
Research has demonstrated that Thymalin influences T-cell maturation and differentiation markers in preclinical cell-culture systems. Studies in aged animal research models have shown shifts in thymic-architecture readouts and immune-cell research markers, including CD4/CD8 ratio profiles and natural-killer-cell activity panels. The peptide has also been investigated for its effects on neuroendocrine regulation, with studies suggesting modulation of melatonin production and circadian cortisol patterns.
Long-term observational studies conducted by Khavinson and colleagues have examined Thymalin's effects in elderly cohorts, reporting improvements in immune markers, cardiovascular parameters, and mortality indices over follow-up periods of up to 12 years. These studies, while primarily conducted within Russian research frameworks, have contributed to the growing field of bioregulatory peptide research in gerontology.
Areas of Study
Immune Regulation
Investigated for restoration of thymic function and normalization of T-cell subpopulations in aging and immunodeficiency models.
T-Cell Maturation
Promotes differentiation and functional development of T-lymphocytes through thymic microenvironment support.
Neuroendocrine Function
Studied for modulation of melatonin secretion and cortisol circadian patterns, suggesting thymic-pineal axis interactions.
Aging Research
Preclinical studies in aged animal models have examined effects on immune markers, cardiovascular parameters, and longevity indices.
References
- [1]Khavinson VK. (2002). Peptides and aging. Neuroendocrinology Letters, 23(Suppl 3), 11-144.
- [2]Khavinson VK. (2002). Peptides and Ageing. Neuroendocrinology Letters, 23(Suppl 3), 11-144.
- [3]Kuznik BI, Pateyuk AV, Baranchugova LM, Rusaeva NS. (2013). Thymalin and its role in immunomodulation. Advances in Gerontology, 3(4), 301-305.
- [4]Khavinson VK, Kuznik BI, Ryzhak GA. (2014). Peptide bioregulators: a new class of geroprotectors. Message 1: results of experimental studies. Advances in Gerontology, 4(4), 225-233.
Disclaimer: Information provided for research reference only; not medical advice. Sold strictly for in-vitro research use.
Certificate of Analysis
Third-party verified
Every batch of Thymalin is independently tested by an A2LA-accredited (ISO 17025:2017) laboratory using HPLC-UV/VIS for purity and identity, with a batch-specific lot number. Results are published publicly.
View COAsFrequently
Asked
Questions
Everything on purity, paperwork, shipping and the research-use-only terms. Still stuck? Read the full FAQ.
What does research use only mean?
Every compound we supply is a reference standard intended strictly for in-vitro laboratory research. It is not a drug or a supplement, and it is not for human or veterinary use, nor for diagnostic or therapeutic use.
How is purity verified?
Every lot is assayed by HPLC at an independent, accredited third-party laboratory. We publish the resulting Certificate of Analysis and link it to the lot number printed on the vial.
Where do I find the Certificate of Analysis?
Every lot has a public, batch-linked COA. Browse them all on the COA page, or open any product page and use the COA tab for that specific compound.
How quickly do orders ship?
Orders placed before 2PM EST ship the same business day. Shipments are cold-packed where required and fully tracked.
Do you ship internationally?
We currently ship within the United States. Requests from institutional buyers outside the US are handled case by case, so contact us before ordering.
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