Tesamorelin10mg–20mg
$170Lyophilized Tesamorelin supplied as a research reference standard.
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Supplied to qualified labs and institutional buyers. Institutional use & eligibility
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Example Certificate of Analysis
Certificate of Analysis
Tesamorelin
Lot Number
EXAMPLE-LOT
Purity (HPLC)
≥99%
Nominal Fill
10mg
Illustrative example of the certificate format issued for this compound. Purity and specification figures are the published values for Tesamorelin; the lot number and test date are placeholders, not a real result. The certificate for the specific lot you receive is matched to the lot number printed on the vial. For laboratory research use only.
Characteristics
| Molecular Formula | C₂₂₁H₃₆₆N₇₂O₆₇S |
|---|---|
| CAS Number | 218949-48-5 |
| Molar Mass | 5135.89 g/mol |
| Amino Acid Sequence | Trans-3-hexenoic acid-modified GHRH (1-44)-NH₂ |
| Synonyms | Egrifta (brand), TH9507, Tesamorelin acetate |
| Physical Form | Lyophilized powder |
| Solubility | Soluble in aqueous buffer; reconstitute for in-vitro laboratory use only |
| Organoleptic Profile | White to off-white lyophilized cake or powder; odorless |
| Storage Conditions | Store lyophilized at 2-8°C; use reconstituted research solution promptly |
| Composition | Lyophilized tesamorelin acetate |
How is Tesamorelin used in research?
Tesamorelin is a synthetic analog of growth hormone-releasing hormone (GHRH) consisting of all 44 amino acids of endogenous GHRH with a trans-3-hexenoic acid modification at the N-terminus. This modification enhances the peptide's resistance to enzymatic degradation while preserving full biological activity at the GHRH receptor.
The mechanism involves physiological stimulation of pulsatile GH secretion from the anterior pituitary, which in turn increases hepatic IGF-1 production and promotes lipolysis-assay markers in visceral adipose cell cultures. Preclinical research in rodent models has characterized visceral-fat parameter shifts while subcutaneous adipose tissue, lean-mass readouts, and glucose-tolerance markers are preserved.
Research has also investigated tesamorelin for effects on hepatic-fat-content markers and cognitive-research preclinical models. These studies leverage the known relationship between the GH/IGF-1 axis and hippocampal neurogenesis, synaptic plasticity, and cerebrovascular function in preclinical research models.
Areas of Study
Visceral Adipose Tissue Research
Investigated in preclinical rodent models for visceral-adipose parameter shifts through enhanced GH-mediated lipolysis markers.
Growth Hormone Physiology
Studied as a GHRH analog that modulates pulsatile GH secretion in preclinical models, preserving feedback regulation through somatostatin and IGF-1.
Hepatic Lipid Metabolism
Investigated for hepatic-fat-content marker modulation through enhanced GH-mediated lipid-metabolism assays in preclinical steatosis research models.
Neuroprotective Assay Models
Preclinical research explores whether GH-axis modulation shifts cognitive-research markers through hippocampal neurogenesis assays and synaptic-plasticity models.
Preclinical Metabolic Parameters
Research examines visceral-fat-parameter shifts in rodent models while lean-mass and subcutaneous-adipose readouts are preserved, unique to GHRH-based preclinical approaches.
References
- [1]Ferdinando C, Bowers CY. (2010). Growth hormone-releasing hormone (GHRH) analogs stimulate GH secretion and have metabolic effects in animal models. Growth Hormone & IGF Research, 20(3), 186-193.
- [2]Gaylinn BD, Thorner MO. (2001). GHRH receptors, secretagogue receptors, and GH secretion. Growth Hormone & IGF Research, 11(Suppl A), S35-S38.
- [3]Murray RD, Shalet SM. (2000). Growth hormone: current and future therapeutic applications. Expert Opinion on Pharmacotherapy, 1(5), 975-990.
Disclaimer: Information provided for research reference only; not medical advice. Sold strictly for in-vitro research use.
Certificate of Analysis
Third-party verified
Every batch of Tesamorelin is independently tested by an A2LA-accredited (ISO 17025:2017) laboratory using HPLC-UV/VIS for purity and identity, with a batch-specific lot number. Results are published publicly.
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Asked
Questions
Everything on purity, paperwork, shipping and the research-use-only terms. Still stuck? Read the full FAQ.
What does research use only mean?
Every compound we supply is a reference standard intended strictly for in-vitro laboratory research. It is not a drug or a supplement, and it is not for human or veterinary use, nor for diagnostic or therapeutic use.
How is purity verified?
Every lot is assayed by HPLC at an independent, accredited third-party laboratory. We publish the resulting Certificate of Analysis and link it to the lot number printed on the vial.
Where do I find the Certificate of Analysis?
Every lot has a public, batch-linked COA. Browse them all on the COA page, or open any product page and use the COA tab for that specific compound.
How quickly do orders ship?
Orders placed before 2PM EST ship the same business day. Shipments are cold-packed where required and fully tracked.
Do you ship internationally?
We currently ship within the United States. Requests from institutional buyers outside the US are handled case by case, so contact us before ordering.
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